Thomas Stanley, 2nd Earl of Derby (c. 1477-23 May 1521), was an English peer. Derby was the eldest son of George Stanley (jure uxoris 9th Baron Strange) and Joan Strange, 9th Baroness Strange and 5th Baroness Mohun. Thomas Stanley, 1st Earl of Derby was his grandfather. His father had been summoned to Parliament as Lord Strange in 1482 in right of his wife, but predeceased his father. Derby succeeded his grandfather in the earldom and barony of Stanley in 1504, and in 1514, he also inherited the baronies of Strange and Mohun from his mother. He married Anne Hastings-daughter of Edward Hastings, 2nd Baron Hastings-in about 1507. Lord Derby died in May 1521 and was succeeded in his titles by his son Edward. His line of the Stanley family failed on the death of James Stanley, 10th Earl of Derby in 1736, when the earldom passed on to a descendant of his younger brother, Sir James Stanley, who founded the branch of the family known as the "Stanleys of Bickerstaffe."